TLR9 Antibody (2A4C6.2E5) [DyLight 755]

Name: TLR9 Antibody (2A4C6.2E5) [DyLight 755]
Brand: Novus Biologicals
SKU: NBP2-31150IR
Price: 489 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-31150IR

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Product Documents

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ICC/IF (Negative)

Label

DyLight 755 (Excitation = 754 nm, Emission = 776 nm)

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # 2A4C6.2E5

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Product Specifications

Immunogen

Partial recombinant protein made to an internal portion of mouse TLR9 (between amino acids 500-800) [UniProt Q9EQU3]

Localization

Endoplasmic reticulum membrane, Endosome, Lysosome, Cytoplasmic vesicle/phagosome.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Applications for TLR9 Antibody (2A4C6.2E5) [DyLight 755]

Application

Recommended Usage

ICC/IF (Negative)

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TLR9

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TLR9 is strictly dependent on MyD88.

Long Name

Toll-like Receptor 9

Alternate Names

CD289

Gene Symbol

TLR9

Additional TLR9 Products

Product Documents for TLR9 Antibody (2A4C6.2E5) [DyLight 755]

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Product Specific Notices for TLR9 Antibody (2A4C6.2E5) [DyLight 755]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.