ZBTB5 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76518

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ZBTB6. The immunogen is located within the last 50 amino acids of ZBTB5.

Specificity

At least two isoforms of ZBTB5 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZBTB5 Antibody - BSA Free

Western Blot: ZBTB5 AntibodyBSA Free [NBP1-76518]

Western Blot: ZBTB5 AntibodyBSA Free [NBP1-76518]

Western Blot: ZBTB5 Antibody [NBP1-76518] - Mouse brain tissue lysate with ZBTB5 antibody at (A) 1 and (B) 2 ug/mL.
ZBTB5 Antibody - BSA Free

Immunohistochemistry: ZBTB5 Antibody - BSA Free [NBP1-76518] -

Immunohistochemistry: ZBTB5 Antibody - BSA Free [NBP1-76518] - Immunohistochemistry of ZBTB5 in human brain tissue with ZBTB5 antibody at 2.5 ug/mL.
ZBTB5 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: ZBTB5 Antibody - BSA Free [NBP1-76518] -

Immunocytochemistry/ Immunofluorescence: ZBTB5 Antibody - BSA Free [NBP1-76518] - Immunofluorescence of ZBTB5 in human brain tissue with ZBTB5 antibody at 20 ug/mL.

Applications for ZBTB5 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZBTB5

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.

Alternate Names

KIAA0354, zinc finger and BTB domain containing 5, zinc finger and BTB domain-containing protein 5

Gene Symbol

ZBTB5

Additional ZBTB5 Products

Product Documents for ZBTB5 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for ZBTB5 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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