24 results for "Compounds for ESC/iPSC Cell Differentiation Small Molecules and Peptides" in 产品

Compounds for ESC/iPSC Cell Differentiation Small Molecules and Peptides

Embryonic stem cells (ESCs) are found in the inner cell mass of blastocysts. They are considered immortal as they have an unlimited capacity for self-renewal in an undifferentiated state. ESCs have the ability to differentiate into cells from all three germ layers (endoderm, mesoderm and ectoderm).

Embryonic stem cells (ESCs) are pluripotent cells and differentiation is tightly controlled by growth factor, cytokines and Epigenetic processes such as DNA methylation and chromatin remodeling. ...

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Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names: Compound C,BML-275
Chemical Name: 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity: ≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor
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Endogenous retinoic acid receptor agonist

Alternate Names: Tretinoin,ATRA
Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Purity: ≥98%
iPSC differentiation with retinoic acid
(2)
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Highly potent PORCN inhibitor

Chemical Name: 4-(2-Methyl-4-pyridinyl)-N-[4-(3-pyridinyl)phenyl]benzeneacetamide
Purity: ≥99%
Highly potent PORCN inhibitor
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CK1 inhibitor

Chemical Name: N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride
Purity: ≥99%
CK1 inhibitor
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XAV 939 synthesized to cGMP guidelines

Chemical Name: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity: ≥99%
XAV 939 synthesized to cGMP guidelines
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Selective covalent PPARγ antagonist

Chemical Name: 2-Chloro-5-nitro-N-phenylbenzamide
Purity: ≥98%
Selective covalent PPARγ antagonist
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Endogenous agonist for the transcription factor aryl hydrocarbon receptor

Alternate Names: Aryl hydrocarbon receptor ligand
Chemical Name: 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester
Purity: ≥98%
Endogenous agonist for the transcription factor aryl hydrocarbon receptor
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Potent inhibitor of Wnt/β-catenin signaling

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity: ≥98%
Potent inhibitor of Wnt/β-catenin signaling
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Histone deacetylase inhibitor

Chemical Name: Butanoic acid sodium salt
Histone deacetylase inhibitor
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Adenosine deaminase inhibitor

Chemical Name: erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride
Purity: ≥98%
Adenosine deaminase inhibitor
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Induces definitive endoderm formation in mouse and human ESCs

Chemical Name: 1-[2-[(2-Carboxyphenyl)methylene]hydrazide]heptanoic acid
Purity: ≥98%
Induces definitive endoderm formation in mouse and human ESCs
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Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

Chemical Name: N-Cyclopropyl-5-(2-thienyl)-3-isoxazolecarboxamide
Purity: ≥98%
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
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Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes

Chemical Name: N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide
Purity: ≥98%
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
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Synthetic retinoid; induces differentiation of stem cells

Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid
Purity: ≥99%
Synthetic retinoid; induces differentiation of stem cells
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A 83-01 synthesized to Ancillary Material Grade

Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity: ≥98%
A 83-01 synthesized to Ancillary Material Grade
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SCD-1 inhibitor

Alternate Names: NSC 14613
Chemical Name: 4-Pyridinecarboxylic acid 2-phenylhydrazide
Purity: ≥99%
SCD-1 inhibitor
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Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

Chemical Name: 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline hydrochloride
Purity: ≥97%
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
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Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells

Chemical Name: 5,5'-[(2-Hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid] disodium salt
Purity: ≥98%
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
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Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation

Chemical Name: 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol
Purity: ≥97%
Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation
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T3 synthesized to Ancillary Material Grade

Chemical Name: O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
Purity: ≥98%
TB6666-RMU vial
(2)
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Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes

Chemical Name: 2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one
Purity: ≥98%
Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes
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Glutathione (GSH) precursor; maintains stem cell function in culture.

Chemical Name: (2R)-2-Acetamido-3-sulfanylpropanoic acid
Purity: ≥98%
Adult Stem Cell-derived Lung Organoids
(5)
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Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water

Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥97%
Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water
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Retinoic acid synthesized to Ancillary Material Grade

Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid
Purity: ≥98%
Retinoic acid synthesized to Ancillary Material Grade
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