53 results for "Compounds for Stem Cell Differentiation" in 产品

Compounds for Stem Cell Differentiation

Stem cell differentiation involves the changing of a cell to a more specialized cell type, involving a switch from proliferation to specialization. This involves a succession of alterations in cell morphology, membrane potential, metabolic activity and responsiveness to certain signals. Differentiation leads to the commitment of a cell to developmental lineages and the acquisition of specific functions of committed cells depending upon the tissue in which they will finally reside. Stem cell ...

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DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds

Alternate Names: Methyl sulfoxide
Chemical Name: Dimethyl sulfoxide
Purity: ≥99.9%
DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds
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Adenylyl cyclase activator

Alternate Names: Coleonol,Colforsin
Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity: ≥98%
Adult Stem Cell-derived Liver Organoids
(2)
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Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP
GMP
Alternate Names: LDN 193189 2HCl
Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)
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Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names: Compound C,BML-275
Chemical Name: 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity: ≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor
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γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity: ≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)
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AMPK activator

Chemical Name: N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide
Purity: ≥99%
AMPK activator
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Selective JNK inhibitor

Chemical Name: Anthra[1-9-cd]pyrazol-6(2H)-one
Purity: ≥98%
Selective JNK inhibitor
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Anti-inflammatory glucocorticoid

Chemical Name: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥98%
Anti-inflammatory glucocorticoid
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Forskolin synthesized to Ancillary Material Grade

Chemical Name: (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
Purity: ≥98%
Forskolin synthesized to Ancillary Material Grade
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High affinity PKC activator; also APP modulator

Chemical Name: (2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide
Purity: ≥98%
High affinity PKC activator; also APP modulator
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Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.

Alternate Names: SIK inhibitor 1
Chemical Name: 1-(2,4-Dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)urea
Purity: ≥98%
Potent pan-salt inducible kinases (SIK1, SIK2 and SIK3) inhibitor. Also inhibits Lat-B-induced EP differentiation via nuclear YAP1 accumulation.
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DAPT synthesized to Ancillary Material Grade

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity: ≥99%
DAPT synthesized to Ancillary Material Grade
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Endogenous retinoic acid receptor agonist

Alternate Names: Tretinoin,ATRA
Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Purity: ≥98%
iPSC differentiation with retinoic acid
(2)
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Activator of LKB1/AMPK; antidiabetic agent

Chemical Name: N,N-Dimethylimidodicarbonimidic diamide hydrochloride
Activator of LKB1/AMPK; antidiabetic agent
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Selective ALK2 inhibitor

Chemical Name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Purity: ≥98%
Selective ALK2 inhibitor
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FGFR1 and -3 inhibitor

Chemical Name: N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Purity: ≥98%
FGFR1 and -3 inhibitor
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Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs

Chemical Name: 2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt
Purity: ≥95%
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
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Potent AMPK activator

Chemical Name: 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Purity: ≥98%
Potent AMPK activator
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Endogenous agonist of LPA1 and LPA2

Chemical Name: 1-O-9Z-Octadecenoyl-sn-glyceryl-3-phosphoric acid sodium salt
Endogenous agonist of LPA1 and LPA2
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Smo receptor agonist

Chemical Name: 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine
Purity: ≥98%
applications of purmorphamine in neurons derived from hiPSCs
(2)
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Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Chemical Name: O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity: ≥98%
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
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5-HT reuptake inhibitor

Chemical Name: N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenylpropylamine hydrochloride
Purity: ≥98%
5-HT reuptake inhibitor
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CK1 inhibitor

Chemical Name: N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride
Purity: ≥99%
CK1 inhibitor
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Histone deacetylase inhibitor

Chemical Name: Butanoic acid sodium salt
Histone deacetylase inhibitor
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Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs

Chemical Name: N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt
Purity: ≥98%
Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs
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