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20 results for "Other Degraders Small Molecules and Peptides" in 产品
Other Degraders Small Molecules and Peptides
Selective peptide-based β-catenin Degrader (PROTAC®)
| Purity: | ≥95% |
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Potent MIF Degrader (PROTAC®)
| Chemical Name: | 8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4-(7-hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)octanamide |
| Purity: | ≥98% |
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Potent PARP1 Degrader (PROTAC®)
| Chemical Name: | N-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide |
| Purity: | ≥98% |
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Mitochondrial targeting AUTAC Degrader
| Chemical Name: | N-[(16R)-16-[[[2-Amino-9-[(4-fluorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]methyl]-15,18-dioxo-4,7,10-trioxa-14,17-diazanonadec-1-yl]-α-oxo-2-phenyl-1H-indole-3-acetamide |
| Purity: | ≥98% |
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Potent and selective USP7 Degrader (PROTAC®)
| Chemical Name: | 3-(1-(1-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidine-4-carbonyl)piperidin-4-yl)-N-(3-((4-hydroxy-1-((R)-3-phenylbutanoyl)piperidin-4-yl)methyl)-4-oxo-3,4-dihydroquinazolin-7-yl)propanamide |
| Purity: | ≥96% |
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Potent and selective nicotinamide phosphoribosyl transferase (NAMPT) Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((S)-18-(tert-Butyl)-1,16-dioxo-1-(4-((4-((4-(3-(pyridin-3-ylmethyl)thioureido)phenyl)sulfonyl)piperazin-1-yl)methyl)phenyl)-5,8,11,14-tetraoxa-2,17-diazanonadecan-19-oyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
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Potent human carbonic anhydrase II Degrader (PROTAC®)
| Chemical Name: | 4-(Aminosulfonyl)-N-[12-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]dodecyl]benzamide |
| Purity: | ≥98% |
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Potent hematopoietic prostaglandin D2 synthase Degrader (PROTAC®)
| Chemical Name: | N-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1-piperazinyl]carbonyl]-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide |
| Purity: | ≥98% |
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α-synuclein Degrader (PROTAC®)
| Chemical Name: | 2-[[3-[5-(1,3-Benzodioxol-5-yl)-1H-pyrazol-3-yl]phenyl]amino]-N-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]acetamide |
| Purity: | ≥98% |
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Selective STING Degrader (PROTAC®)
| Chemical Name: | (2E)-N1-[6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide |
| Purity: | ≥98% |
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Potent lactate dehydrogenase Degrader (PROTAC®)
| Chemical Name: | 2-(5-(Cyclopropylmethyl)-3-(3-(6-(13-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-13-oxotridecanamido)hex-1-yn-1-yl)phenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid |
| Purity: | ≥98% |
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NSD2 Degrader (PROTAC®)
| Chemical Name: | N-Cyclopropyl-N-(4-((5-(3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamido)propoxy)pyridin-2-yl)-carbamoyl)benzyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide |
| Purity: | ≥98% |
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Selective PRMT5 Degrader (PROTAC®)
| Chemical Name: | N-((S)-3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-((1-((S)-19-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidine-1-carbonyl)-20,20-dimethyl-17-oxo-3,6,9,12,15-pentaoxa-18-azahenicosanoyl)azetidin-3-yl)amino)pyrimidine-4-carboxamide |
| Purity: | ≥98% |
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Potent NSD2 Degrader
| Chemical Name: | N-[[4-[[[2-(6-Amino-1-oxohexyl)-1,2,3,4-tetrahydro-6-isoquinolinyl]amino]carbonyl]phenyl]methyl]-N-cyclopropyl-3,4-dihydro-3-oxo-2H-1,4-benzoxazine-7-carboxamide trifluoroacetate |
| Purity: | ≥98% |
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SARS-CoV-2 Mpro Degrader (PROTAC®)
| Chemical Name: | 3-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)oxy)benzyl ((2S,3R)-3-(tert-butoxy)-1-(((S)-3-cyclohexyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)propan-2-yl)amino)-1-oxobutan-2-yl)carbamate |
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PDEδ autophagy-tethering compound (ATTEC) Degrader
| Chemical Name: | N-(6-(2-(2,6-Dibromo-4-((5-iodo-2-oxoindolin-3-ylidene)methyl)phenoxy)acetamido)hexyl)-4-(3,4-dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide |
| Purity: | ≥98% |
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Potent and selective AR and AR L702H Degrader, orally bioavailable
| Chemical Name: | 4-[4-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-7-methoxy-1-oxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]phenyl]-1-piperidinyl]-3-fluoro-2-(trifluoromethyl)benzonitrile |
| Purity: | ≥98% |
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MAGE-A3 Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-N-(2-(2-(2-(2-((4-(Furan-2-carbonyl)piperazin-1-yl)methyl)-4-(1H-indazol-4-yl)phenoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
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Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins
| Chemical Name: | N1-(4-(((2-Amino-6-chloropyrimidin-4-yl)oxy)methyl)benzyl)-N7-((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)heptanediamide |
| Purity: | ≥98% |
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Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins
| Chemical Name: | N-(4-(((2-Amino-6-chloropyrimidin-4-yl)oxy)methyl)benzyl)-2-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidin-4-yl)acetamide |
| Purity: | ≥97% |
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