2-Furoyl-LIGRLO-amide
Tocris Bioscience | Catalog # 3015
Potent and selective PAR2 agonist
Loading...
Key Product Details
Description
Potent and selective PAR2 agonist
Product Description
2-Furoyl-LIGRLO-amide is a potent and selective PAR2 receptor agonist (pD2 = 7.0). Causes a dose-dependent relaxation of murine femoral arteries.
Product Specifications for 2-Furoyl-LIGRLO-amide
Molecular Weight
777.96
Formula
C36H63N11O8
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
729589-58-6
PubChem ID
10395438
InChI Key
OSKIRYSKGDEIOG-WTWMNNMUSA-N
SMILES
[H]N([C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN)C(N)=O)C(=O)C1=CC=CO1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Loading...
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.
- Alshurafa A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH2, induces protease release from mast cells: role in TNF degradation. BMC Pharmacol. 2004 PMID: 15265236
- Olianas Proteinase-activated receptors 1 and 2 in rat olfactory system: layer-specific regulation of multiple signaling pathways in the main olfactory bulb and induction of neurite retraction in olfactory sensory neurons. Neuroscience 2007 PMID: 17434682
- McGuire 2-Furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist. J.Pharmacol.Exp.Ther. 2004 PMID: 14976230
Product Documents for 2-Furoyl-LIGRLO-amide
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for 2-Furoyl-LIGRLO-amide
For research use only
Citations for 2-Furoyl-LIGRLO-amide
Customer Reviews for 2-Furoyl-LIGRLO-amide (1)
5 out of 5
1 Customer Rating
Have you used 2-Furoyl-LIGRLO-amide?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Showing
1
-
1 of
1 review
Showing All
Filter By:
-
Species: MouseAssay Type: Ex VivoVerified Customer | Posted 09/20/2019Used this compound on an ex-vivo experiment. Tissue: Mouse colon. 2F caused massive PAR2 receptor internalization in the colonic mucosa. Very easy to dissolve, great and potent PAR2 Agonist.ex-vivo mouse colonic tissue
There are no reviews that match your criteria.
Loading...