3',3'-cGAMP sodium salt
Chemical Name: 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
Biological ActivitySTING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice.
This product is sold in units of 359μg, equivalent to 0.5μmol.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
- This product is sold in units of 359μg, equivalent to 0.5μmol.
Agonist-mediated activation of STING induces apoptosis in malignant B cells.
Tang et al.
Cancer Res., 2016;76:2137
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