Catalog Number: 5946
Chemical Name: 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
Biological Activity
STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 10 mM in water
  • Purity:
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
  • This product is sold in units of 359μg, equivalent to 0.5μmol.
Background References
  1. Agonist-mediated activation of STING induces apoptosis in malignant B cells.
    Tang et al.
    Cancer Res., 2016;76:2137
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