Potent and selective GSK-3β
values are 34 and 304 nM in the presence of 10 and 100 μ
M ATP respectively).
Soluble to 25 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Characterization and development of novel small-molecules inhibiting GSK3 and activating wnt signaling.
Zhong et al.
Benzo[e]isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode.
Zou et al.