4-DAMP

  ( 14 citations )    
Product Datasheet
Catalog Number:0482
Chemical Name:1,1-Dimethyl-4-diphenylacetoxypiperidinium iodide
Product Details
Citations (14)
Supplemental Products
Reviews
Biological Activity
Antagonist at the M3 cholinergic receptor. [3H]-4-DAMP selectively labels M1 and M3 receptors.
Technical Data
  • M.Wt:
    451.33
  • Formula:
    C21H26INO2
  • Solubility:
    Soluble to 25 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    1952-15-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for 4-DAMP include:

14 Citations: Showing 1 - 10
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  1. Regulation of nerve-evoked contractions of rabbit vas deferens by acetylcholine.
    Authors: Wallace Et al.
    Microvasc Res  2015;3
  2. Diadenosine tetraphosphate contributes to carbachol-induced tear secretion.
    Authors: Fonseca Et al.
    Purinergic Signal  2015;11:87
  3. M2 Muscarinic acetylcholine receptor modulates rat airway smooth muscle cell proliferation.
    Authors: Placeres-Uray Et al.
    World Allergy Organ J  2014;6:22
  4. Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
    Authors: Nedvetsky Et al.
    Dev Cell  2014;30:449
  5. M2muscarinic receptors inhibit cell proliferation and migration in urothelial bladder cancer cells.
    Authors: Pacini Et al.
    Cancer Biol Ther  2014;15:1489
  6. An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats.
    Authors: Mans Et al.
    J Neurophysiol  2014;112:2388
  7. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.
    Authors: Jahchan Et al.
    Cancer Discov  2013;3:1364
  8. Muscarinic type 3 receptor induces cytoprotective signaling in salivary gland cells through epidermal growth factor receptor transactivation.
    Authors: Kajiya Et al.
    J Neurosci  2012;82:115
  9. Signaling pathways used by EGF to stimulate conjunctival goblet cell secretion.
    Authors: Hodges Et al.
    Exp Eye Res  2012;103:99
  10. Differential roles of M2 and M3 muscarinic receptor subtypes in modulation of bladder afferent activity in rats.
    Authors: Matsumoto Et al.
    Urology  2010;75:862
  11. M3 muscarinic receptors mediate positive inotropic responses in mouse atria: a study with muscarinic receptor knockout mice.
    Authors: Kitazawa Et al.
    Mol Pharmacol  2009;330:487
  12. Cholinergic innervation of the guinea-pig isolated vas deferens.
    Authors: Solanki Et al.
    Naunyn Schmiedebergs Arch Pharmacol  2007;376:265
  13. Coregulation of natively expressed pertussis toxin-sensitive muscarinic receptors with G-protein-activated potassium channels.
    Authors: Clancy Et al.
    Physiol Rep  2007;27:6388
  14. In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine.
    Authors: Howell Et al.
    BMC Pharmacol  2005;5:13
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