Catalog Number: 0748
Chemical Name: N-(N-Benzylpiperidin-4-yl)-4-iodobenzamide
Biological Activity
Combines high affinity for σ1 and moderate affinity for σ2 sites. Centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
    420.29
  • Formula:
    C19H21IN2O
  • Solubility:
    Soluble to 10 mM in DMSO and to 5 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Desiccate at +4°C
  • CAS No:
    155798-08-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Modulation of serotonergic neurotransmission by short- and long-term treatments with sigma ligands
    Bermack and Debonnel
    Br.J.Pharmacol., 2001;134:691
  2. Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition.
    Whittemore et al.
    J.Pharmacol.Exp.Ther., 1997;282:326
  3. Synthesis and characterisation of [125I]-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide, a new sigma receptor radiopharmaceutical: high affinity binding to MCF-7 breast tumor cells.
    John et al.
    J.Med.Chem., 1994;37:1737

Have you used 4-IBP?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information