4-IBP

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Antagonism of N-MthD.-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition.
   Whittemore et al.
   J.Pharmacol.Exp.Ther., 1997;282:326
3. Modulation of serotonergic neurotransmission by short- and long-term treatments with sigma ligands
   Bermack and Debonnel
   Br.J.Pharmacol., 2001;134:691
4. Synthesis and characterisation of [¹²⁵I]-N-(N-benzylpiperidin-4-yl)-4-iodobenzamide, a new sigma receptor radiopharmaceutical: high affinity binding to MCF-7 breast tumor cells.
   John et al.
   J.Med.Chem., 1994;37:1737

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