4μ8C

Catalog # Availability Size / Price Qty
4479/10
4479/50
4μ8C | CAS No. 14003-96-4 | IRE1 Inhibitors
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Description: Inhibits IRE1α endoribonuclease activity

Chemical Name: 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde

Purity: ≥98%

Product Details
Citations (2)
Reviews

Biological Activity

Selective inhibitor of IRE1α ribonuclease (RNase) activity (IC50 = 60 nM). Blocks substrate access to the active site of IRE1α. Inactivates IRE1α-mediated mRNA degradation. Displays no effect on the IRE1α-related endoribonuclease RNase L.

Technical Data

M.Wt:
204.18
Formula:
C11H8O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
14003-96-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for 4μ8C

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