Catalog Number: 1481
Alternate Names: (-)-5'-Dimethylheptyl-cannabidiol
Chemical Name: 5-(1,1-Dimethylheptyl)-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol
Biological Activity
Anandamide membrane transport inhibitor (IC50 = 14 μM) that is relatively metabolically stable. Displays some affinity for CB2 receptors but has only weak affinity for CB1 receptors and has no activity at VR1 receptors or FAAH. Anticonvulsive in vivo following systemic administration.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.
    Bisogno et al.
    Br.J.Pharmacol., 2001;134:845
  2. Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs.
    Leite et al.
    Pharmacology, 1982;24:141
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