Chemical Name:5-(2-Aminoethyl)-1,2,4-benzenetriol hydrobromide
Biological Activity Selective catecholaminergic neurotoxin. Depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease.
Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at -20°C
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