Catalog Number: 0719
Alternate Names: 7-OH-PIPAT
Chemical Name: (RS)-trans-7-Hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin maleate
Biological Activity
This ligand has uniquely high affinity and selectivity for the D3 receptor. 8-Hydroxy-PIPAT maleate (Cat. No. 0797) also available.
Technical Data
  • M.Wt:
    487.33
  • Formula:
    C16H22INO.C4H4O4
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Desiccate at +4°C
  • CAS No:
    200722-46-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of the University of Pennsylvania
Other Product-Specific Information:
Background References
  1. Synthesis and optical resolution of (R)- and (S)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin: a new D3 dopamine receptor ligand.
    Chumpradit et al.
    J.Med.Chem., 1993;36:4308
  2. Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand.
    Foulon et al.
    J.Med.Chem., 1993;36:1499
  3. In vitro binding of a novel dopamine D3 receptor ligand: [125I]-trans-7-OH-PIPAT.
    Kung et al.
    Eur.J.Pharmacol., 1993;235:165

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