A 68930 hydrochloride
Chemical Name: cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
Biological ActivityA 68930 hydrochloride is a potent and selective D1-like dopamine receptor agonist (EC50 values are 2.1 and 3910 nM for D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Psychopharmacological distinction between novel full-efficacy "D1-like" DA receptor agonists.
Deveney and Waddingto
A68930: a potent and specific agonist for the D-1 DA receptor.
Kebabian et al.
(1R,3S)-1-(Aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist.
Quaglia et al.
Citations for A 68930 hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for A 68930 hydrochloride include:
3 Citations: Showing 1 - 3
The DA D1 receptor is expressed and facilitates relaxation in airway smooth muscle.
Authors: Mizuta Et al.
PLoS One 2013;14:89
Phosphorylation of mouse melanopsin by protein kinase A.
Authors: Blasic Et al.
Sci Rep 2012;7:e45387
Stimulation of the D5 DA receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
Authors: Guha Et al.
J Neurochem 2012;122:823
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