Catalog Number: 1534
Chemical Name: cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
Biological Activity
Potent and selective D1-like dopamine receptor agonist (EC50 values are 2.1 and 3910 nM for D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in water
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Psychopharmacological distinction between novel full-efficacy "D1-like" dopamine receptor agonists.
    Deveney and Waddingto
    Pharmacol.Biochem.Behav., 1997;58:551
  2. A68930: a potent and specific agonist for the D-1 dopamine receptor.
    Kebabian et al.
    Am.J.Hypertens., 1990;3:40S
  3. (1R,3S)-1-(Aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist.
    Quaglia et al.
    J.Med.Chem., 1990;33:2948

The citations listed below are publications that use Tocris products. Selected citations for A 68930 hydrochloride include:

Showing Results 1 - 3 of 3

  1. The dopamine D1 receptor is expressed and facilitates relaxation in airway smooth muscle.
    Authors: Mizuta Et al.
    PLoS One
  2. Phosphorylation of mouse melanopsin by protein kinase A.
    Authors: Blasic Et al.
    Sci Rep
  3. Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
    Authors: Guha Et al.
    J Neurochem
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information