Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs). Prevents opening of nicotinic receptor-associated ion channels and is selective for α
7 receptors over α
4 receptors (IC50
values are 1.6 nM and > 3 μ
(Modifications: Disulfide bridge between 3 - 23, 16 - 44, 29 - 33, 48 - 59, 60 - 65)
Soluble in water
Desiccate at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels.
Zhang et al.
Unmasking the functions of the chromaffin cell α7 nicotinic receptor by using short pulses of acetylcholine and selective blockers.
Lopez et al.
The citations listed below are publications that use Tocris products. Selected citations for α-Bungarotoxin include:
Showing Results 1 - 10 of 18