AA 2414
Chemical Name: 7-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoic acid
Purity: ≥98%
Biological Activity
Thromboxane A2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA2 mimetic in guinea pigs.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids.
Ashida et al.
Prostaglandins, 1989;38:91 -
Antagonism of the human thromboxane A2 receptor by an anti-asthmatic agent AA-2414.
Kurokawa et al.
Biol.Pharm.Bull., 1994;17:383 -
Leukotrienes and cyclooxygenase products mediate anaphylactic venoconstriction in ovalbumin sensitized rat livers.
Cui et al.
Eur.J.Pharmacol., 2007;576:99
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for AA 2414
The citations listed below are publications that use Tocris products. Selected citations for AA 2414 include:
1 Citation: Showing 1 - 1
-
The receptor antagonist picotamide inhibits adrenergic and thromboxane-induced contraction of hyperplastic human prostate smooth muscle.
Authors: Hennenberg Et al.
Am J Physiol Renal Physiol 2013;305:F1383
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsVersaClone cDNA Plasmids
Reviews for AA 2414
There are currently no reviews for this product. Be the first to review AA 2414 and earn rewards!
Have you used AA 2414?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
