ABT 702 dihydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:2372
Chemical Name:5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyrido[2,3-d]byrimidin-4-amine dihydrochloride
Product Details
Citations (2)
Reviews
Biological Activity
Potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in animal models of pain and inflammation.
Technical Data
  • M.Wt:
    536.26
  • Formula:
    C22H19N6OBr.2HCl
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    1188890-28-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for ABT 702 dihydrochloride include:

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  1. Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in rats.
    Authors: Hobson Et al.
    Neuropharmacology  2012;63:1172
  2. Adenosine kinase regulation of cardiomyocyte hypertrophy.
    Authors: Fassett Et al.
    Am J Physiol Heart Circ Physiol  2011;300:H1722

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