Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, promotes detachment of neutrophils from activated mesenteric endothelium and accelerates epithelial wound repair after induced colonic injury in mice in vivo
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Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody.
Perretti et al.
Annexin 1: an endogenous anti-inflammatory protein.
Perretti and Gavins
News Physiol.Sci., 2003;18:60
Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1.
Lim et al.
Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.
Leoni et al.
The citations listed below are publications that use Tocris products. Selected citations for Ac2-26 include:
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