ADWX 1

   
Product Datasheet
Catalog Number:4812
Chemical Name:
Product Details
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Biological Activity
Potent and selective KV1.3 channel blocker (IC50 values are 0.0019 and 0.65 nM for KV1.3 and KV1.1, respectively). Inhibits CD4+ CCR7- T cell activation. Ameliorates rat experimental autoimmune encephalomyelitis, in a model for multiple sclerosis.
Technical Data
  • M.Wt:
    4071.86
  • Formula:
    C169H281N57O46S7
  • Sequence:
    VGINVKCKHSRQCLKPCKDAGMRFGKCTNGKCHCTPK

    (Modifications: Disulfide bridge: 7 - 27, 13 - 32, 17 - 34)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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