Chemical Name: [(3,4-Dihydroxyphenyl)methylene]-propenedinitrile
Biological Activity Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 μM respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling.
Desiccate at +4°C
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