AGAP2 Antibody

Novus Biologicals | Catalog # NBP2-24498

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Canine, Equine, Primate

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Cited:

Western Blot, Immunocytochemistry/ Immunofluorescence, Knockdown Validated

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all AGAP2 Primary Antibodies »

Product Specifications

Immunogen

A portion of amino acids 450-500 of human AGAP2 was used as the immunogen.

Reactivity Notes

Opossum (86%).

Specificity

100% homologous to Human (isoform CRA_a).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AGAP2 Antibody

Western Blot: AGAP2 Antibody [NBP2-24498]

Western Blot: AGAP2 Antibody [NBP2-24498]

Western Blot: AGAP2 Antibody [NBP2-24498] - Analysis of AGAP2 in Jurkat cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: AGAP2 Antibody [NBP2-24498]

Immunohistochemistry-Paraffin: AGAP2 Antibody [NBP2-24498]

Immunohistochemistry-Paraffin: AGAP2 Antibody [NBP2-24498] - Analysis human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Applications for AGAP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

reported in scientific literature (PMID 34411567)

Immunohistochemistry-Paraffin

5 ug/ml

Knockdown Validated

reported in scientific literature (PMID 34411567)

Western Blot

1-3 ug/ml

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AGAP2

AGAP2 (also known as centaurin-gamma1, ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Phosphatidyl-inositol-3-kinase enhancer, PIKE, GTP-binding and GTPase activating protein 2 and GGAP2) is a GTPase activating protein that inactivates Arf. The expression of AGAP2 is amplified in human glioblastoma cells. AGAP2 protein binds to and activates the protein kinase Akt and prevents apoptosis of cancer cells. AGAP2 also increases motility and invasive activity of cancer cells. AGAP2 may serve as a diagnostic and therapeutic target of human cancer.

Alternate Names

AGAP-2, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2, arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, centaurin, gamma 1, Centaurin-gamma-1, CENTG1, Cnt-g1, FLJ16430, GGAP2, GTP-binding and GTPase activating protein 2, GTP-binding and GTPase-activating protein 2, KIAA0167, Phosphatidylinositol-3-kinase enhancer, phosphoinositide 3-kinase enhancer, PIKEArf GAP with GTP-binding protein-like, ANK repeat and PH domains 2

Gene Symbol

AGAP2

Additional AGAP2 Products

Product Documents for AGAP2 Antibody

Certificate of Analysis

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Product Specific Notices for AGAP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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