Alfacalcidol

Catalog # Availability Size / Price Qty
4159/1
Additional VDR-like Receptor Compounds Small Molecule
1 Image
Description: Prodrug of vitamin D3 (Cat. No. 4156)
Alternative Names: 1-Hydroxycholecalciferol

Chemical Name: (1α,3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol

Purity: ≥97%

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Biological Activity

Metabolite and prodrug of vitamin D3 (Cat. No. 4156). Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.

Technical Data

M.Wt:
400.64
Formula:
C27H44O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
41294-56-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen.
    Shiraishi et al.
    Journal of Bone and Mineral Research., 2000;15:770

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