ALK/CD246 Antibody (7A11A4) - BSA Free

Novus Biologicals | Catalog # NBP2-61845

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 7A11A4

Format

BSA Free
View all ALK/CD246 Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human ALK/CD246 (AA: 1366-1468) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for ALK/CD246 Antibody (7A11A4) - BSA Free

Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Analysis using ALK mAb against human ALK (AA: 1366-1468) recombinant protein. (Expected MW is 36.9 kDa)
Immunocytochemistry/ Immunofluorescence: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

Immunocytochemistry/ Immunofluorescence: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

Immunocytochemistry/Immunofluorescence: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Analysis of Hela cells using ALK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.
Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4)BSA Free [NBP2-61845]

Western Blot: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Analysis using ALK mAb against HEK293 (1) and ALK (AA: 1366-1468)-hIgGFc transfected HEK293 (2) cell lysate.
ELISA: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

ELISA: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

ELISA: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
ELISA: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

ELISA: ALK/CD246 Antibody (7A11A4) - BSA Free [NBP2-61845]

ELISA: ALK/CD246 Antibody (7A11A4) [NBP2-61845] - Analysis of Hela cells using ALK mouse mAb (green) and negative control (red).

Applications for ALK/CD246 Antibody (7A11A4) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Immunocytochemistry/ Immunofluorescence

1:50-1:250

Western Blot

1:500-1:2000

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALK/CD246

This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).;

Long Name

Anaplastic Lymphoma Kinase

Alternate Names

CD246, Ki-1, Tcrz

Gene Symbol

ALK

Additional ALK/CD246 Products

Product Documents for ALK/CD246 Antibody (7A11A4) - BSA Free

Certificate of Analysis

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Product Specific Notices for ALK/CD246 Antibody (7A11A4) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Receptor Tyrosine Kinases (RTKs)

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Protocols

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FAQs

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