α-helical CRF 9-41
Tocris Bioscience | Catalog # 1184
CRF antagonist
Discontinued Product
1184 has been discontinued.
View all Non-selective CRF Receptor Antagonists products.
Key Product Details
Description
CRF antagonist
Alternative Names
α-helical-Corticotropin-Releasing Factor 9-41
Product Description
α-helical CRF 9-41 is a corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).Licensing Information
Sold with the permission of the SALK Institute
Product Specifications for α-helical CRF 9-41
Molecular Weight
3827.00
Formula
C166H274N46O53S2
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
90880-23-2
PubChem ID
44593730
InChI Key
PNGVJHODDQMQKT-GVKLFNHCSA-N
SMILES
[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in 0.1M NH4OH |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.
- Perrin and Vale Corticotropin releasing factor receptors and their ligand family. Ann.N.Y.Acad.Sci. 1999 PMID: 10816663
- Swerdlow Potentiation of acoustic startle by corticotropin-releasing factor (CRF) and by fear are both reversed by α-helical CRF (9-41). Neuropsychopharmacology 1989 PMID: 2610824
- Kask Alpha-helical(9-41) revents anxiogenic-like effect of NPY Y1 receptor antagonist BIBP3226. NeuroReport 1997 PMID: 9427342
Product Documents for α-helical CRF 9-41
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for α-helical CRF 9-41
For research use only
Related Research Areas
Citations for α-helical CRF 9-41
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Assay Type: In VitroCell Line/Tissue: placental cytotrophoblastVerified Customer | Posted 05/31/2018cell treatment
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