α-Methyl-5-hydroxytryptamine maleate

Name: α-Methyl-5-hydroxytryptamine maleate
Brand: Tocris Bioscience
SKU: 0557

Tocris Bioscience | Catalog # 0557

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Citations (3)

Product Documents

5-HT2B agonist

Discontinued Product

0557 has been discontinued. View all 5-HT2B Receptor Agonists products.

Product Description
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

5-HT2B agonist

View all 5-HT2B Receptor Agonists »

Product Description

5-HT_2B receptor selective agonist with pK_i values of 8.4, 6.1 and 7.3 at 5-HT_2B, 5-HT_2A and 5-HT_2C receptors respectively.

Product Specifications for α-Methyl-5-hydroxytryptamine maleate

Molecular Weight

306.32

Formula

C₁₁H₁₄N₂O.C₄H₄O₄

Storage

Store at -20°C

Purity

≥98% (HPLC)

CAS Number

97469-12-0

PubChem ID

9922558

InChI Key

YQNHFSXRABPJLP-BTJKTKAUSA-N

SMILES

OC(=O)\C=C/C(O)=O.CC(N)CC1=CNC2=C1C=C(O)C=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water		10
	DMSO	30.63	100

Preparing Stock Solutions for α-Methyl-5-hydroxytryptamine maleate

The following data is based on the product molecular weight 306.32.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.26 mL	16.32 mL	32.65 mL
5 mM	0.65 mL	3.26 mL	6.53 mL
10 mM	0.33 mL	1.63 mL	3.26 mL
50 mM	0.07 mL	0.33 mL	0.65 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

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M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Concentration 1 (C1)

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Concentration 2 (C2)

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Richardson Identification of serotonin M-receptor sub-types and their specific blockade by a new class of drugs. Nature 1985 PMID: 3839291
Wilson 5-Hydroxytryptamine₃ receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 1990 PMID: 1968974
Baxter 5-HT₂ receptor subtypes: a family re-united? TiPS 1995 PMID: 7792930

Product Documents for α-Methyl-5-hydroxytryptamine maleate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for α-Methyl-5-hydroxytryptamine maleate

For research use only

Citations for α-Methyl-5-hydroxytryptamine maleate

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