Catalog Number: 0557
Biological Activity
5-HT2B receptor selective agonist with pKi values of 8.4, 6.1 and 7.3 at 5-HT2B, 5-HT2A and 5-HT2C receptors respectively.
Technical Data
  • M.Wt:
    306.32
  • Formula:
    C11H14N2O.C4H4O4
  • Solubility:
    Soluble to 10 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    97469-12-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. 5-HT2 receptor subtypes: a family re-united?
    Baxter et al.
    TiPS, 1995;16:105
  2. Identification of serotonin M-receptor sub-types and their specific blockade by a new class of drugs.
    Richardson et al.
    Nature, 1985;316:126
  3. 5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs.
    Wilson et al.
    J.Pharmacol.Exp.Ther., 1990;252:683
Citations:

The citations listed below are publications that use Tocris products. Selected citations for α-Methyl-5-hydroxytryptamine maleate include:

1 Citations: Showing 1 - 1

  1. Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling.
    Authors: Coulon Et al.
    Front Cell Neurosci 2011;4:132

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