AM 630

Tocris Bioscience | Catalog # 1120

Selective CB2 inverse agonist
Tocris Bioscience

Key Product Details

Description

Selective CB2 inverse agonist
View all Cannabinoid R2 / CB2 Inverse Agonists »

Product Description

AM 630 is a CB2 inverse agonist (Ki = 31.2 nM) that displays 165-fold selectivity over CB1 receptors. Behaves as a weak partial/inverse agonist at CB1 receptors.

Product Specifications for AM 630

Molecular Weight

504.37

Formula

C23H25IN2O3

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

6-Iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)methanone

CAS Number

164178-33-0

PubChem ID

4302963

InChI Key

JHOTYHDSLIUKCJ-UHFFFAOYSA-N

SMILES

COC1=CC=C(C=C1)C(=O)C1=C(C)N(CCN2CCOCC2)C2=CC(I)=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 50.44 100

Preparing Stock Solutions for AM 630

The following data is based on the product molecular weight 504.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.98 mL 9.91 mL 19.83 mL
5 mM 0.40 mL 1.98 mL 3.97 mL
10 mM 0.20 mL 0.99 mL 1.98 mL
50 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 432 publications citing the usage of this product.

Product Documents for AM 630

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for AM 630

For research use only

Customer Reviews for AM 630

There are currently no reviews for this product. Be the first to review AM 630 and earn rewards!

Have you used AM 630?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card