Catalog Number: 0789
Chemical Name: (±)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate
Biological Activity
A potent nicotinic agonist (Ki values are 1.25 and 1840 nM for α4β2 and α7 nicotinic receptors respectively). Stimulates [3H]-dopamine release from rat striatal synaptosomes (EC50 = 136 nM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in water
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Induced release of acetylcholine from guinea pig ileum longitudinal muscle myenteric plexus by anatoxin-A.
    Gordon et al.
    J.Pharmacol.Exp.Ther., 1992;263:997
  2. Behavioural effects of anatoxin, a potent nicotinic agonist in rats.
    Stolerman et al.
    Neuropharmacology, 1992;31:311
  3. (+)-Anatoxin is a potent agonist at neuronal nicotinic acetylcholine receptors.
    Thomas et al.
    J.Neurochem., 1993;60:2308
  4. UB-165 implicates α4β2 nAChR in striatal dopamine release.
    Sharples et al.
    J.Neurosci., 2000;20:2783

The citations listed below are publications that use Tocris products. Selected citations for (±)-Anatoxin A fumarate include:

1 Citations: Showing 1 - 1

  1. Effect of nitrogen on cellular production and release of the neurotoxin anatoxin-a in a nitrogen-fixing cyanobacterium.
    Authors: Gagnon and Pick
    Front Microbiol 2012;3:211

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