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APcK 110

Catalog #: 3704 Datasheet / COA / SDS

Discontinued Product

3704 has been discontinued.
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APcK 110 | CAS No. 1001083-74-4 | Additional RTK Inhibitors
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Description: KIT inhibitor

Chemical Name: 6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine

Purity: ≥98%

Product Details
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Biological Activity

KIT inhibitor; inhibits phosphorylation of KIT, STAT3, STAT5 and Akt. Suppresses proliferation of OCI/AML3 cells (IC50 = 175 nM). Caspase-dependant apoptosis inducer.

Technical Data

M.Wt:
349.36
Formula:
C20H16FN3O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1001083-74-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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