Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

PerCP (Excitation = 490 nm, Emission = 675 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 665404
View all APH1A Primary Antibodies »

Product Specifications

Immunogen

Human APH1A synthetic peptide
SSFERFEIFPKHVTDRSDARLQY
Accession # Q96BI3

Specificity

Detects human APH1A in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for APH1A Antibody (665404) [PerCP]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: APH1A

Anterior Pharynx Defective 1 (APH1a) is an integral transmembrane protein forming a component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein).

Long Name

gamma-Secretase Subunit Anterior Pharynx Defective 1 Homolog A

Alternate Names

6530402N02Rik, anterior pharynx defective 1 homolog A (C. elegans), APH-1, APH-1A, Aph-1alpha, CGI-78, gamma-secretase subunit APH-1A, Presenilin-stabilization factor, PSF

Gene Symbol

APH1A

Additional APH1A Products

Product Documents for APH1A Antibody (665404) [PerCP]

Certificate of Analysis

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Product Specific Notices for APH1A Antibody (665404) [PerCP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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