APH1A: Products

Anterior pharynx-defective 1 (APH1A) is a widely expressed 36 kDa 7-transmembrane protein found in the endoplasmic reticulum and Golgi. APH1A is a component of the gamma secretase proteolytic complex which cleaves multiple substrates within their transmembrane domains.

"APH1A" has 11 results in Products.
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Gamma γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling


DAPT synthesized to Ancillary Material Grade


γ-secretase inhibitor; inhibits Notch pathway

Human APH1A Antibody 

BMS 299897 

Potent γ-secretase inhibitor

MRK 560 

γ-secretase inhibitor; attenuates amyloid plaque deposition

PF 3084014 hydrobromide 

Potent γ-secretase inhibitor


Highly potent γ-secretase inhibitor; orally bioavailable

LY 450139 

γ-secretase pseudo-inhibitor
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