Apicidin

Catalog # Availability Size / Price Qty
4846/1
Cat.No. 4846 - Apicidin | C34H49N5O6 | CAS No. 183506-66-3
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Description: Potent histone deacetylase inhibitor

Chemical Name: Cyclo[(2S)-2-Amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]

Purity: ≥98%

Product Details
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Biological Activity

Potent histone deacetylase (HDAC) inhibitor (IC50 = 0.7 nM in an enzyme activity assay). Antiangiogenic and anti-invasive; blocks proliferation of human stomach and breast cancer cells. Induces apoptosis and autophagy in human oral squamous carcinoma cells.

Technical Data

M.Wt:
623.78
Formula:
C34H49N5O6
Solubility:
Soluble to 2 mM in DMSO and to 2 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
183506-66-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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