Apigenin

  ( 1 citations )    
Product Datasheet
Catalog Number:1227
Chemical Name:5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Product Details
Citations (1)
Reviews
Biological Activity
Protein kinase inhibitor. Suppresses tumor-promoting effects of TPA and exhibits antiproliferative activity in human breast cancer cells (IC50 values are 59.44 and 31.15 μM at 24 and 72 hrs respectively). Activates both the intrinsic and extrinsic apoptotic pathways and displays anti-inflammatory, hypotensive, antispasmodic and antioxidant properties in vivo.
Technical Data
  • M.Wt:
    270.2
  • Formula:
    C15H10O5
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
    >97
  • Storage:
    Desiccate at +4°C
  • CAS No:
    520-36-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Apigenin include:

1 Citations: Showing 1 - 1

  1. Growth inhibition and apoptosis by (-)-epicatechin gallate are mediated by cyclin D1 suppression in head and neck squamous carcinoma cells.
    Authors: Lim Et al.
    J Neurosci  2006;42:3260

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