AR-R 17779 hydrochloride

Catalog # Availability Size / Price Qty
3964/10
Nicotinic (a7) Receptor Agonists Small Molecule
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Description: Selective α7 nAChR agonist

Chemical Name: (3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidine]-2'-one hydrochloride

Product Details
Citations (1)
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Biological Activity

Selective agonist of α7 nAChRs (Ki values are 190 and 16000 nM for rat α7 and α4β2 receptors respectively). CNS penetrant after systemic administration.

Technical Data

M.Wt:
218.68
Formula:
C9H14N2O2.HCl
Solubility:
Soluble to 50 mM in DMSO and to 100 mM in water
Storage:
Desiccate at RT
CAS No:
178419-42-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.

Product Datasheets

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Citation for AR-R 17779 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for AR-R 17779 hydrochloride include:

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