Catalog Number: 0389
Chemical Name: N,N'-1,4-Butanediylbisguanidine sulfate
Biological Activity
NO synthase inhibitor. An NMDA antagonist acting as a competitive inhibitor at the polyamine site.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Investigation of the actions and antagonist activity of some polyamine analogues in vivo.
    Doyle and Shaw
    Br.J.Pharmacol., 1998;124:386
  2. Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor.
    Eur.J.Pharmacol., 1990;177:215
  3. Structure-activity relationships of arginine analogues on nitric oxide synthase activity in the rat brain.
    Yokoi et al.
    Neuropharmacology, 1994;33:1261
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