Home / Synthase/Synthetase Inhibitors / AT 56

AT 56

Catalog #: 3531
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3531/10
3531/50
AT 56 | CAS No. 162640-98-4 | Synthase/Synthetase Inhibitors
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Description: L-PGDS inhibitor

Chemical Name: 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

AT 56 is an orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) (Ki = 75 μM, IC50 = 95 μM). Inhibits the production of PGD2 from PGH2 in vitro, with no effect on PGE2 or PGF2α production.

Technical Data

M.Wt:
397.52
Formula:
C25H27N5
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
162640-98-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for AT 56

The citations listed below are publications that use Tocris products. Selected citations for AT 56 include:

1 Citation: Showing 1 - 1

  1. Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport.
    Authors: Jaurena Et al.
    Elife  2015;6:7476

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