Catalog Number: 1688
Alternate Names: AIP
Biological Activity
Selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor (IC50 = 40 nM). Selective over PKC, PKA and CaM kinase IV (IC50 > 10 μM).
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II.
    Ishida et al.
    Biochem.Biophys.Res.Commun., 1995;212:806
  2. Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain.
    Ishida and Fujisawa
    J.Biol.Chem., 1995;270:2163
  3. Requirement of calmodulin-dependent protein kinase II in cyclic ADP-ribose-mediated intracellular Ca2+ mobilization.
    Takasawa et al.
    J.Biol.Chem., 1995;270:30257

The citations listed below are publications that use Tocris products. Selected citations for Autocamtide-2-related inhibitory peptide include:

1 Citations: Showing 1 - 1

  1. Pituitary adenylate cyclase-activating polypeptide induces postsynaptically expressed potentiation in the intra-amygdala circuit.
    Authors: Cho Et al.
    J Neurosci 2012;32:14165

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