Catalog Number: 5796
Chemical Name: N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide
Biological Activity
Modulator of unfolded protein response (UPR). Protects cells from ER stress by improving ER protein folding and activating ER chaperone capacity. Also improves ER calcium retention. Improves liver ER function, glucose homeostasis and glucose-stimulated insulin secretion in mouse obesity models. Orally bioavailable.
Technical Data
  • M.Wt:
    308.83
  • Formula:
    C15H17ClN2OS
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    932986-18-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.
    Fu et al.
    Sci.Transl.Med., 2015;7:292ra98

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