Chemical Name: 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline
Biological ActivityB2 is a promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease. Prevents mutant huntingtin-mediated proteasome dysfunction and reduces α-synuclein-mediated toxicity.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parksinson's diseases.
Bodner et al.
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