BADGE

  ( 1 citations )    
Product Datasheet
Catalog Number:1326
Alternate Names:Bisphenol A diglycidyl ether
Chemical Name:2,2-Bis[4-(2,3-epoxypropoxy)phenyl]propane
Product Details
Citations (1)
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Reviews
Biological Activity
PPARγ pure antagonist with micromolar affinity in 3T3-L1 and 3T3-F442A preadipocyte cells; selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARγ. Acts as a PPARγ agonist in an ECV304 cell line. Also produces PPARγ-independent apoptosis of tumor cells via several mechanisms. Active in vivo.
Technical Data
  • M.Wt:
    340.42
  • Formula:
    C21H24O4
  • Solubility:
    Soluble to 50 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >95
  • Storage:
    Desiccate at -20°C
  • CAS No:
    1675-54-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for BADGE include:

1 Citations: Showing 1 - 1

  1. Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor γ in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo.
    Authors: Hegde Et al.
    J Immunol  2015;194:5211

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