Batimastat

Tocris Bioscience | Catalog # 2961

Potent, broad spectrum MMP inhibitor
Tocris Bioscience

Key Product Details

Description

Potent, broad spectrum MMP inhibitor

Alternative Names

BB-94
View all Synthetic Metalloprotease Inhibitors »

Product Description

Batimastat is a potent, broad spectrum MMP inhibitor (IC50 values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human ovarian carcinoma xenografts in vivo.

Product Specifications for Batimastat

Molecular Weight

477.64

Formula

C23H31N3O4S2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide

CAS Number

130370-60-4

PubChem ID

5362422

InChI Key

XFILPEOLDIKJHX-QYZOEREBSA-N

SMILES

O=[C@]([C@H](CC(C)C)[C@@H]([C@](NO)=O)CSC2=CC=CS2)N[C@H](C(NC)=O)CC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.76 100

Preparing Stock Solutions for Batimastat

The following data is based on the product molecular weight 477.64.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.09 mL 10.47 mL 20.94 mL
5 mM 0.42 mL 2.09 mL 4.19 mL
10 mM 0.21 mL 1.05 mL 2.09 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 84 publications citing the usage of this product.

Product Documents for Batimastat

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Batimastat

For research use only

Customer Reviews for Batimastat (1)

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  • works well
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Hippocampal neuron
    Verified Customer | Posted 03/26/2020
    matrix metalloproteinases 1, 2, 3, 7, 9, 14, and 17 (0.1–1 μM batimastat and marimastat)
    Batimastat 2961

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