Potent, broad spectrum MMP inhibitor (IC50
values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human ovarian carcinoma xenografts in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts.
Davies et al.
Cancer Res., 1993;53:2087
Matrix metalloproteinase inhibitor BB-94 (Batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice.
Wang et al.
Cancer Res., 1994;54:4726
Molecular insights into cancer invasion: strategies for prevention and intervention.
Kohn and Liotta
Cancer Res., 1995;55:1856
The citations listed below are publications that use Tocris products. Selected citations for Batimastat include:
Showing Results 1 - 10 of 19