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BAY-u 9773

Catalog #: 3138
1 Citation Datasheet / COA / SDS

Discontinued Product

3138 has been discontinued.
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BAY-u 9773 | CAS No. 154978-38-8 | Leukotriene and Related Receptor Antagonists
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Description: Dual CysLT1 and CysLT2 antagonist

Chemical Name: 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Cysteinyl leukotriene receptor antagonist with equal affinity at both CysLT1 and CysLT2 receptors (pKB values are 6.8 and 6.5 respectively). Competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea.

Technical Data

M.Wt:
472.64
Formula:
C27H36O5S
Solubility:
Soluble in ethanol (supplied pre-dissolved in Ethanol, 0.1mg/ml)
Storage:
Store at -80°C
CAS No:
154978-38-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A second cysteinyl leukotriene receptor in human lung.
    Labat et al.
    J.Pharmacol.Exp.Ther., 1992;263:800
  2. Cysteinyl leukotriene receptors in the human lung: what's new?
    Goranne et al.
    TiPS, 1996;17:342
  3. Functional characteristics of cysteinyl-leukotriene receptor subtypes.
    Back
    Life Sci., 2002;71:611

Product Datasheets

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Citation for BAY-u 9773

The citations listed below are publications that use Tocris products. Selected citations for BAY-u 9773 include:

1 Citation: Showing 1 - 1

  1. Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome.
    Authors: Wegner Et al.
    Elife  2019;8

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