Catalog Number: 3138
Chemical Name: 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid
Biological Activity
Cysteinyl leukotriene receptor antagonist with equal affinity at both CysLT1 and CysLT2 receptors (pKB values are 6.8 and 6.5 respectively). Competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble in ethanol (supplied pre-dissolved in Ethanol, 0.1mg/ml)
  • Storage:
    Store at -80°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Cysteinyl leukotriene receptors in the human lung: what's new?
    Goranne et al.
    TiPS, 1996;17:342
  2. Functional characteristics of cysteinyl-leukotriene receptor subtypes.
    Life Sci., 2002;71:611
  3. A second cysteinyl leukotriene receptor in human lung.
    Labat et al.
    J.Pharmacol.Exp.Ther., 1992;263:800
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