Catalog Number: 0906
Chemical Name: 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropylamino-2-propanol hydrochloride
Biological Activity
Selective β1-adrenoceptor antagonist.
Technical Data
  • M.Wt:
    343.89
  • Formula:
    C18H29NO3.HCl
  • Solubility:
    Soluble to 50 mM in water
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    63659-19-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension.
    Beresford and Heel
    Drugs, 1986;31:6
  3. Inhibitory action of betaxolol, a β1-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea pig artery and vein.
    Setoguchi et al.
    Br.J.Pharmacol., 1995;115:198
  4. The affinity of betaxolol, a β1-adrenoceptor-selective blocking agent, for β-adrenoceptors in the bovine trachea and heart
    Satoh et al.
    Br.J.Pharmacol., 1993;108:484
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Betaxolol hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands.
    Authors: Littmann Et al.
    Cardiovasc Res 2015;355:183
  2. β1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons.
    Authors: Meitzen Et al.
    J Neurochem 2011;116:984

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