BIM 23056
1 Image
Description: sst ligand
Biological Activity
Somatostatin receptor ligand (Ki values are 142, > 1000, 10.8, 16.6 and 5.7 nM for human cloned sst1 - 5 receptors respectively). Behaves as an antagonist on SRIF14-induced [35S]-GTPγS binding at sst3 and sst5 receptors (PKB values are 6.33 and 5.84 respectively).Technical Data
M.Wt:
1232.49
Formula:
C71H81N11O9
Sequence:
FFYWKVFX
(Modifications: Phe-1 = D-Phe, Trp-4 = D-Trp, X = D-Nal & C-terminal amide)
Solubility:
Soluble to 1 mg/ml in 20% acetonitrile / water
Storage:
Desiccate at -20°C
CAS No:
150155-61-6
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).
Patel and Srikant
Endocrinology, 1994;135:2814 -
Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.
Raynor et al.
Mol.Pharmacol., 1993;43:838 -
Characterisation of human recombinant somatostatin receptors. Modulation of GTPgammaS binding.
Siehler and Hoyer
Naunyn Schmiedebergs Arch.Pharmacol., 1999;360:500 -
Potent antagonism by BIM-23056 at the human recombinant somatostatin sst5 receptor.
Wilkinson et al.
Br.J.Pharmacol., 1996;118:445
Product Datasheets
or select another batch:
Reconstitution Calculator
Molarity Calculator
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsReviews for BIM 23056
There are currently no reviews for this product. Be the first to review BIM 23056 and earn rewards!
Have you used BIM 23056?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris Bioscience is the leading supplier of novel and exclusive
tools for
life science research with over 30 years' experience in the
industry.
Tocris is a Bio-Techne brand.
