Catalog Number: 1383
Alternate Names: Indomethacin morpholinylamide, IMMA
Chemical Name: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole
Biological Activity
Potent and selective CB2 receptor ligand (Ki values are 435 nM and > 2 μM for CB2 and CB1 respectively).
Technical Data
  • M.Wt:
    426.9
  • Formula:
    C23H23ClN2O4
  • Solubility:
    Soluble to 100 mM in DMSO with gentle warming
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    2854-32-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation.
    Melck et al.
    Endocrinology, 2000;141:118
  2. New class of potent ligands for the human peripheral cannabinoid receptor.
    Gallant et al.
    Bioorg.Med.Chem.Lett., 1996;6:2263

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