BMP-15/GDF-9B Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-81743

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all BMP-15/GDF-9B Primary Antibodies »

Product Specifications

Immunogen

Rabbit polyclonal BMP15 antibody was raised against an 18 amino acid peptide near the amino terminus of human BMP15. The immunogen is located within amino acids 60 - 110 of BMP15. Amino Acid Squence: LYRRSADSHGHPRENRTI

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse: (89%), Sheep: (83%), Bovine: (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BMP-15/GDF-9B Antibody - BSA Free

Immunohistochemistry: BMP-15/GDF-9B Antibody - BSA Free [NBP2-81743]

Immunohistochemistry: BMP-15/GDF-9B Antibody - BSA Free [NBP2-81743]

Immunohistochemistry: BMP-15/GDF-9B Antibody [NBP2-81743] - Analysis of BMP-15/GDF-9B in human prostate tissue with BMP-15/GDF-9B antibody at 10 ug/ml.

Applications for BMP-15/GDF-9B Antibody - BSA Free

Application
Recommended Usage

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BMP-15/GDF-9B

 

BMP-15 (Bone morphogenetic protein 15), also known as GDF-9B, is a TGF-b superfamily ligand that is expressed by oocytes throughout folliculogenesis and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis. BMP-15 blocks the FSH-induced GC expression of FSH R and multiple steroidogenic molecules. BMP-15 exerts is effects through interactions with BMPR-IB/ALK6 and BMPR-II, and nonphosphorylated BMP-15 functions as a competitive antagonist at BMPR-IB. Mature BMP-15 forms 34 kDa noncovalently-linked homodimers and 37 kDa heterodimers with mature GDF-9.

Long Name

Bone Morphogenetic Protein 15

Alternate Names

BMP15, GDF-9B

Gene Symbol

BMP15

Additional BMP-15/GDF-9B Products

Product Documents for BMP-15/GDF-9B Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for BMP-15/GDF-9B Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

BMP Family

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Protocols

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