BNTX maleate

Name: BNTX maleate
Brand: Tocris Bioscience
SKU: 0899

Catalog #: 0899
1 Citation Datasheet / COA / SDS

Discontinued Product

0899 has been discontinued.

View all delta Opioid Receptor Antagonists products.

BNTX maleate | CAS No. 864461-31-4 | delta Opioid Receptor Antagonists

1 Image

Description: Standard δ1 selective antagonist

Chemical Name: 7-Benzylidenenaltrexone maleate

Purity: ≥99%

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Product Details

Citations (1)

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

BNTX maleate is a standard selective δ₁ opioid receptor antagonist. Also inhibits neurogenic ion transport mediated by a putative novel opioid receptor in porcine ileal mucosa.

Technical Data

M.Wt:

545.59

Formula:

C₂₇H₂₇NO₄.C₄H₄O₄

Solubility:

Soluble to 100 mM in DMSO and to 10 mM in water with gentle warming

Purity:

≥99%

Storage:

Desiccate at -20°C

CAS No:

864461-31-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
Antinociception and d-1 opioid receptors in the rat spinal cord: studies with intrathecal 7-benzylidenenaltrexone.
Hammond et al.
J.Pharmacol.Exp.Ther., 1995;274:1317
Pharmacological evidence for a 7-benzylidenenaltrexone-preferring opioid receptor mediating the inhibitory actions of peptidic δ- and μ-opioid agonists on neurogenic ion transport in porcine ileal mucosa.
Poonyachoti et al.
J.Pharmacol.Exp.Ther., 2001;297:672
A δ₁-opioid receptor antagonist: 7-benzylidenenaltrexone.
Portoghese et al.
Eur.J.Pharmacol., 1992;218:195

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for BNTX maleate

The citations listed below are publications that use Tocris products. Selected citations for BNTX maleate include:

1 Citation: Showing 1 - 1

Heterodimerization of μ and δ opioid receptors: A role in opiate synergy.
Authors: Gomes Et al.
J Cereb Blood Flow Metab 2000;20:RC110

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