Catalog Number: 0899
Chemical Name: 7-Benzylidenenaltrexone maleate
Biological Activity
Standard selective δ1 opioid receptor antagonist. Also inhibits neurogenic ion transport mediated by a putative novel opioid receptor in porcine ileal mucosa.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in water with gentle warming
  • Purity:
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Antinociception and d-1 opioid receptors in the rat spinal cord: studies with intrathecal 7-benzylidenenaltrexone.
    Hammond et al.
    J.Pharmacol.Exp.Ther., 1995;274:1317
  2. A δ1-opioid receptor antagonist: 7-benzylidenenaltrexone.
    Portoghese et al.
    Eur.J.Pharmacol., 1992;218:195
  3. Pharmacological evidence for a 7-benzylidenenaltrexone-preferring opioid receptor mediating the inhibitory actions of peptidic δ- and μ-opioid agonists on neurogenic ion transport in porcine ileal mucosa.
    Poonyachoti et al.
    J.Pharmacol.Exp.Ther., 2001;297:672

The citations listed below are publications that use Tocris products. Selected citations for BNTX maleate include:

Showing Results 1 - 1 of 1

  1. Heterodimerization of μ and δ opioid receptors: A role in opiate synergy.
    Authors: Gomes Et al.
    J Cereb Blood Flow Metab
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