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BRD 7116

Catalog #: 5336 Datasheet / COA / SDS

Discontinued Product

5336 has been discontinued.
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BRD 7116 | CAS No. 329059-55-4 | Stem Cell Signaling Compounds
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Description: Inhibitor of leukemia stem cell activity

Chemical Name: N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]

Purity: ≥98%

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Biological Activity

Inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM). Exhibits >100-fold selectivity for LSCs over normal hematopoietic stem cells.

Technical Data

M.Wt:
496.66
Formula:
C28H36N2O4S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
329059-55-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
    Hartwell et al.
    Nat.Chem.Biol., 2013;9:840

Product Datasheets

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