Chemical Name: N,N'-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
Biological ActivityInhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM). Exhibits >100-fold selectivity for LSCs over normal hematopoietic stem cells.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
Hartwell et al.
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