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Bucindolol

Catalog #: 2658 Datasheet / COA / SDS

Discontinued Product

2658 has been discontinued.
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Bucindolol | CAS No. 71119-11-4 | Non-selective Adrenergic beta Receptor Antagonists
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Description: β1 and β2 antagonist
Alternative Names: MJ 13105

Chemical Name: 2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile

Purity: ≥99%

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Biological Activity

Non-selective β-adrenoceptor antagonist with additional α1-adrenoceptor blocking activity. Ki values are 1.61, 1.20 and 68.9 nM for β1-, β2- and α1-adrenoceptors respectively. Also acts as a weak 5-HT2A/2B antagonist. Displays vasodilatory and antihypertensive actions.

Technical Data

M.Wt:
363.45
Formula:
C22H25N3O2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
71119-11-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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