Chemical Name: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea
Biological ActivityPotent, selective inhibitor of 5-lipoxygenase. Long half-life and high oral bioavailability in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Hydroxamic acids and hydroxyureas as novel, selective 5-lipoxygenase inhibitors for possible use in asthma.
Payne et al.
Agents Actions Suppl., 1991;34:189
Effect of BW B70C, a novel inhibitor of arachidonic acid 5-lipoxygenase, on allergen-induced bronchoconstriction and late-phase lung eosinophil accumulation in sensitised guinea-pigs.
Yeadon et al.
Agents Actions, 1993;38:8
Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents.
Salmon et al.
Citation for BW-B 70C
The citations listed below are publications that use Tocris products. Selected citations for BW-B 70C include:
1 Citation: Showing 1 - 1
Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation.
Authors: Ruparel Et al.
J Cell Biol 2012;153:2031
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