Catalog Number: 1304
Chemical Name: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea
Biological Activity
Potent, selective inhibitor of 5-lipoxygenase. Long half-life and high oral bioavailability in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 3 mM in ethanol and to 3 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Hydroxamic acids and hydroxyureas as novel, selective 5-lipoxygenase inhibitors for possible use in asthma.
    Payne et al.
    Agents Actions Suppl., 1991;34:189
  2. Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents.
    Salmon et al.
    Adv.Prost.Throm.Leuk.Res., 1990;21:109
  3. Effect of BW B70C, a novel inhibitor of arachidonic acid 5-lipoxygenase, on allergen-induced bronchoconstriction and late-phase lung eosinophil accumulation in sensitised guinea-pigs.
    Yeadon et al.
    Agents Actions, 1993;38:8

The citations listed below are publications that use Tocris products. Selected citations for BW-B 70C include:

Showing Results 1 - 1 of 1

  1. Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation.
    Authors: Ruparel Et al.
    J Cell Biol
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